The use of NaCl addition for the improvement of polyhydroxyalkanoate production by Cupriavidus necator

Pearl Passanha, Gopal Kedia, Richard M. Dinsdale, Alan J. Guwy, Sandra R. Esteves

Research output: Contribution to journalArticlepeer-review

Abstract

External stress factors in the form of ionic species or temperature increases have been shown to produce a stress response leading to enhanced PHA production. The effect of five different NaCl concentrations, namely 3.5, 6.5, 9, 12 and 15 g/l NaCl on PHA productivity using Cupriavidus necator has been investigated alongside a control (no added NaCl). A dielectric spectroscopy probe was used to measure PHA accumulation online in conjunction with the chemical offline analysis of PHA. The highest PHA production was obtained with the addition of 9 g/l NaCl, which yielded 30% higher PHA than the control. Increasing the addition of NaCl to 15 g/l was found to inhibit the production of PHA. NaCl addition can therefore be used as a simple, low cost, sustainable, non toxic and non reactive external stress strategy for increasing PHA productivity.
Original languageEnglish
Pages (from-to)287-294
JournalBioresource Technology
Volume163
DOIs
Publication statusPublished - 1 Jul 2014

Keywords

  • Polyhydroxyalkanoate production
  • Cupriavidus necator
  • Sodium chloride
  • Volatile fatty acids
  • Dielectric spectroscopy

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