The impact of medically supervised injection centres on drug-related harms: a meta-analysis

Research output: Contribution to journalArticlepeer-review

41 Downloads (Pure)


Background: Medically Supervised Injection Centres (MSICs) are legally-sanctioned facilities where users can consume
pre-obtained drugs under medical supervision. Although there is a substantial body of research exploring their effectiveness, there have been few attempts to quantify outcomes across studies. In order to determine the impact of the body of research as a whole, outcomes from studies were synthesised using meta-analysis.

Methods: Literature sources were identified through searches in four bibliographic databases. Inclusion in the final review was dependent on the study meeting certain eligibility criteria, including a minimum of pre-test, post-test, control group designs. Data were extracted and pooled in a meta-analysis using both fixed and random effects methods.

Results: Eight studies met the inclusion criteria. Overall, MSICs had a significant, but small, positive effect on outcomes based on the fixed effect analysis and no effect based on random effect analysis. The results of the independent outcome analyses showed that MSICs had a significant favourable result in relation to drug-related crime and a significant unfavourable result in relation to problematic heroin use or injection. MSICs were found
to have no effect on overdose mortality or syringe/equipment sharing.

Conclusion: Whilst the effectiveness of the early versions of MSICs remains uncertain, this should not rule out continuing to test and develop MSICs in locations where public injecting and other drug-related harms are a major problem. It is important, however, that evaluation research publishes replicable data to enable future meta-analyses and to expand the body of knowledge in the field.
Original languageEnglish
Pages (from-to)98-107
JournalInternational Journal of Drug Policy
Issue numberSeptember 2018
Early online date2 Aug 2018
Publication statusPublished - 1 Sept 2018


  • meta-analysis
  • Medically supervised injecting centres
  • Harm-reduction
  • Heroin
  • MSICs
  • Drug Consumption Rooms (DCRs)
  • Safe Injection Sites (SISs)


Dive into the research topics of 'The impact of medically supervised injection centres on drug-related harms: a meta-analysis'. Together they form a unique fingerprint.

Cite this