Solid-phase synthesis of γ-lactams, γ-lactones and cyclobutane derivatives from common resin-bound intermediates

Richard C.d Brown; John Keily; Rehana Karim

doi:10.1016/S0040-4039(00)00359-2

Solid-phase synthesis of γ-lactams, γ-lactones and cyclobutane derivatives from common resin-bound intermediates

Richard C.d Brown, John Keily, Rehana Karim

Research output: Contribution to journal › Article › peer-review

Abstract

Resin-bound cyclobutanone iminium salts, prepared on the solid-phase using the [2+2]-keteneiminium olefin cycloaddition reaction, have been transformed into a number of distinct structural classes including γ-lactams, γ-lactones, cyclobutylamines and cyclobutanols.

Original language	English
Pages (from-to)	3247-3251
Journal	Tetrahedron Letters
Volume	41
Issue number	17
DOIs	https://doi.org/10.1016/S0040-4039(00)00359-2
Publication status	Published - 1 Apr 2000

Keywords

solid-phase synthesis
[2+2] cycloaddition
y-lactams
y-lactones
cyclobutlamines
cyclobutanols
cyclobutanones

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title = "Solid-phase synthesis of γ-lactams, γ-lactones and cyclobutane derivatives from common resin-bound intermediates",

abstract = "Resin-bound cyclobutanone iminium salts, prepared on the solid-phase using the [2+2]-keteneiminium olefin cycloaddition reaction, have been transformed into a number of distinct structural classes including γ-lactams, γ-lactones, cyclobutylamines and cyclobutanols.",

keywords = "solid-phase synthesis, [2+2] cycloaddition, y-lactams, y-lactones, cyclobutlamines, cyclobutanols, cyclobutanones",

author = "Brown, {Richard C.d} and John Keily and Rehana Karim",

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language = "English",

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T1 - Solid-phase synthesis of γ-lactams, γ-lactones and cyclobutane derivatives from common resin-bound intermediates

AU - Brown, Richard C.d

AU - Keily, John

AU - Karim, Rehana

PY - 2000/4/1

Y1 - 2000/4/1

N2 - Resin-bound cyclobutanone iminium salts, prepared on the solid-phase using the [2+2]-keteneiminium olefin cycloaddition reaction, have been transformed into a number of distinct structural classes including γ-lactams, γ-lactones, cyclobutylamines and cyclobutanols.

AB - Resin-bound cyclobutanone iminium salts, prepared on the solid-phase using the [2+2]-keteneiminium olefin cycloaddition reaction, have been transformed into a number of distinct structural classes including γ-lactams, γ-lactones, cyclobutylamines and cyclobutanols.

KW - solid-phase synthesis

KW - [2+2] cycloaddition

KW - y-lactams

KW - y-lactones

KW - cyclobutlamines

KW - cyclobutanols

KW - cyclobutanones

U2 - 10.1016/S0040-4039(00)00359-2

DO - 10.1016/S0040-4039(00)00359-2

M3 - Article

SN - 1873-3581

VL - 41

SP - 3247

EP - 3251

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 17

ER -

Solid-phase synthesis of γ-lactams, γ-lactones and cyclobutane derivatives from common resin-bound intermediates

Abstract

Keywords

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