Mitochondrial free radical formation has been implicated as a potential mechanism underlying degenerative senescence, although human data are lacking. Therefore, the present study was designed to examine if resting and exercise-induced intramuscular free radical-mediated lipid peroxidation is indeed increased across the spectrum of sedentary aging.
- electron paramagnetic resonance spectroscopy
- spin trapping
- lipid peroxidation
- free radical theory of aging