Regulation of Post-Exercise Hemodynamics in Human Ageing: Role of Atrial Natriuretic Peptide and Arginine Vasopressin

Karl New; Bruce Davies; Damian Bailey; M Penney; C Templeton; G Ellis

Regulation of Post-Exercise Hemodynamics in Human Ageing: Role of Atrial Natriuretic Peptide and Arginine Vasopressin

Karl New, Bruce Davies, Damian Bailey, M Penney, C Templeton, G Ellis

Faculty of Life Sciences and Education

Research output: Contribution to conference › Paper › peer-review

Abstract

PURPOSE: Using an acute bout of dynamic exercise the present study sought to determine the influence of the vasoacitive metabolites atrial natruretic peptide (ANP) and arginine vasopressin (AVP) on post-exercise hemodynamics in ageing men.

METHODS: Nine pre-hypertensive males, MAP = 106 ? 5 mmHg (50 ? 10 yr), not on medication, were studied following 30-minutes of cycle exercise at 70% maximal oxygen consumption. The subjects were followed post-exercise for 2-hours. Left ventricular hemodynamics were assessed via echocardiography and systemic vascular resistance (SVR)/vascular conductance (SVC) determined by the quotient of MABP/ and /MABP, respectively. Peripheral venous blood was sampled from an antecubital vein pre-, immediately post-, 1-hour post- (P1) and 2-hours post- (P2) exercise and metabolite concentrations were corrected for plasma volume shifts. ANP and AVP were determined in venous plasma via radioimmunoassay

Original language	English
Publication status	Published - 1 Jan 2009
Event	American College of Sports Medcine 56th Annual Meeting - Washington State Convention and Trade Center, Seattle, United States Duration: 27 May 2009 → 30 May 2009

Conference

Conference	American College of Sports Medcine 56th Annual Meeting
Abbreviated title	ACSM 2009
Country/Territory	United States
City	Seattle
Period	27/05/09 → 30/05/09

Keywords

hemodynamics

Cite this

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title = "Regulation of Post-Exercise Hemodynamics in Human Ageing: Role of Atrial Natriuretic Peptide and Arginine Vasopressin",

abstract = "PURPOSE: Using an acute bout of dynamic exercise the present study sought to determine the influence of the vasoacitive metabolites atrial natruretic peptide (ANP) and arginine vasopressin (AVP) on post-exercise hemodynamics in ageing men. METHODS: Nine pre-hypertensive males, MAP = 106 ? 5 mmHg (50 ? 10 yr), not on medication, were studied following 30-minutes of cycle exercise at 70% maximal oxygen consumption. The subjects were followed post-exercise for 2-hours. Left ventricular hemodynamics were assessed via echocardiography and systemic vascular resistance (SVR)/vascular conductance (SVC) determined by the quotient of MABP/ and /MABP, respectively. Peripheral venous blood was sampled from an antecubital vein pre-, immediately post-, 1-hour post- (P1) and 2-hours post- (P2) exercise and metabolite concentrations were corrected for plasma volume shifts. ANP and AVP were determined in venous plasma via radioimmunoassay",

keywords = "hemodynamics",

author = "Karl New and Bruce Davies and Damian Bailey and M Penney and C Templeton and G Ellis",

year = "2009",

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language = "English",

note = "American College of Sports Medcine 56th Annual Meeting , ACSM 2009 ; Conference date: 27-05-2009 Through 30-05-2009",

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TY - CONF

T1 - Regulation of Post-Exercise Hemodynamics in Human Ageing

T2 - American College of Sports Medcine 56th Annual Meeting

AU - New, Karl

AU - Davies, Bruce

AU - Bailey, Damian

AU - Penney, M

AU - Templeton, C

AU - Ellis, G

PY - 2009/1/1

Y1 - 2009/1/1

N2 - PURPOSE: Using an acute bout of dynamic exercise the present study sought to determine the influence of the vasoacitive metabolites atrial natruretic peptide (ANP) and arginine vasopressin (AVP) on post-exercise hemodynamics in ageing men. METHODS: Nine pre-hypertensive males, MAP = 106 ? 5 mmHg (50 ? 10 yr), not on medication, were studied following 30-minutes of cycle exercise at 70% maximal oxygen consumption. The subjects were followed post-exercise for 2-hours. Left ventricular hemodynamics were assessed via echocardiography and systemic vascular resistance (SVR)/vascular conductance (SVC) determined by the quotient of MABP/ and /MABP, respectively. Peripheral venous blood was sampled from an antecubital vein pre-, immediately post-, 1-hour post- (P1) and 2-hours post- (P2) exercise and metabolite concentrations were corrected for plasma volume shifts. ANP and AVP were determined in venous plasma via radioimmunoassay

AB - PURPOSE: Using an acute bout of dynamic exercise the present study sought to determine the influence of the vasoacitive metabolites atrial natruretic peptide (ANP) and arginine vasopressin (AVP) on post-exercise hemodynamics in ageing men. METHODS: Nine pre-hypertensive males, MAP = 106 ? 5 mmHg (50 ? 10 yr), not on medication, were studied following 30-minutes of cycle exercise at 70% maximal oxygen consumption. The subjects were followed post-exercise for 2-hours. Left ventricular hemodynamics were assessed via echocardiography and systemic vascular resistance (SVR)/vascular conductance (SVC) determined by the quotient of MABP/ and /MABP, respectively. Peripheral venous blood was sampled from an antecubital vein pre-, immediately post-, 1-hour post- (P1) and 2-hours post- (P2) exercise and metabolite concentrations were corrected for plasma volume shifts. ANP and AVP were determined in venous plasma via radioimmunoassay

KW - hemodynamics

M3 - Paper

Y2 - 27 May 2009 through 30 May 2009

ER -

Regulation of Post-Exercise Hemodynamics in Human Ageing: Role of Atrial Natriuretic Peptide and Arginine Vasopressin

Abstract

Conference

Keywords

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