Regulation of Post-Exercise Hemodynamics in Human Ageing: Role of Atrial Natriuretic Peptide and Arginine Vasopressin

Karl New, Bruce Davies, Damian Bailey, M Penney, C Templeton, G Ellis

Research output: Contribution to conferencePaperpeer-review

Abstract

PURPOSE: Using an acute bout of dynamic exercise the present study sought to determine the influence of the vasoacitive metabolites atrial natruretic peptide (ANP) and arginine vasopressin (AVP) on post-exercise hemodynamics in ageing men.

METHODS: Nine pre-hypertensive males, MAP = 106 ? 5 mmHg (50 ? 10 yr), not on medication, were studied following 30-minutes of cycle exercise at 70% maximal oxygen consumption. The subjects were followed post-exercise for 2-hours. Left ventricular hemodynamics were assessed via echocardiography and systemic vascular resistance (SVR)/vascular conductance (SVC) determined by the quotient of MABP/ and /MABP, respectively. Peripheral venous blood was sampled from an antecubital vein pre-, immediately post-, 1-hour post- (P1) and 2-hours post- (P2) exercise and metabolite concentrations were corrected for plasma volume shifts. ANP and AVP were determined in venous plasma via radioimmunoassay
Original languageEnglish
Publication statusPublished - 1 Jan 2009
EventAmerican College of Sports Medcine 56th Annual Meeting - Washington State Convention and Trade Center, Seattle, United States
Duration: 27 May 200930 May 2009

Conference

ConferenceAmerican College of Sports Medcine 56th Annual Meeting
Abbreviated titleACSM 2009
Country/TerritoryUnited States
CitySeattle
Period27/05/0930/05/09

Keywords

  • hemodynamics

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