Internal carotid artery occlusion: its natural history including recanalization and subsequent neurological events

G Morris-Stiff; M Teli; P Y Khan; S O Ogunbiyi; C S Champ; R Hibberd; R Brown; D M Bailey; R K Winter; M H Lewis

doi:10.1177/1538574413500539

Internal carotid artery occlusion: its natural history including recanalization and subsequent neurological events

G Morris-Stiff, M Teli, P Y Khan, S O Ogunbiyi, C S Champ, R Hibberd, R Brown, D M Bailey, R K Winter, M H Lewis

Faculty of Life Sciences and Education

Research output: Contribution to journal › Article › peer-review

Abstract

OBJECTIVE: To determine the incidence of recanalization of the occluded internal carotid artery (ICA) and establish its natural history.

METHODS: Patients with duplex-confirmed ICA occlusions were identified, and a subgroup offered repeat scanning. The antemortem condition and cause of death of patients who died were recorded.

RESULTS: Of 153 patients identified, 77 underwent follow-up at a median of 35 months (interquartile range [IQR]: 14-61).In all, 8 (10.3%) demonstrated recanalization at a median of 53 months (IQR: 35-114). Of 8, 7 underwent carotid endarterectomy with histopathological confirmation of recanalization. Of the 153 patients, 45 (29%) had further neurological events, and 38 (25%) were within the territory of the occluded ICA. In all, 76 patients died, and of the 53 with a confirmed cause of death, 12 (23%) were attributed to a cerebrovascular accident corresponding to the territory of the occluded artery.

CONCLUSION: Recanalization of ICA occlusion is common and leads to significant neurological events. Duplex ultrasound follow-up appears mandatory.

Original language	English
Pages (from-to)	603-7
Number of pages	5
Journal	Vascular and endovascular surgery
Volume	47
Issue number	8
DOIs	https://doi.org/10.1177/1538574413500539
Publication status	Published - Nov 2013

Keywords

Aged
Carotid Artery, Internal
Carotid Stenosis
Cause of Death
Cerebrovascular Disorders
Chronic Disease
Endarterectomy, Carotid
Female
Humans
Male
Middle Aged
Predictive Value of Tests
Recurrence
Risk Factors
Time Factors
Treatment Outcome
Ultrasonography, Doppler, Color

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title = "Internal carotid artery occlusion: its natural history including recanalization and subsequent neurological events",

abstract = "OBJECTIVE: To determine the incidence of recanalization of the occluded internal carotid artery (ICA) and establish its natural history.METHODS: Patients with duplex-confirmed ICA occlusions were identified, and a subgroup offered repeat scanning. The antemortem condition and cause of death of patients who died were recorded.RESULTS: Of 153 patients identified, 77 underwent follow-up at a median of 35 months (interquartile range [IQR]: 14-61).In all, 8 (10.3%) demonstrated recanalization at a median of 53 months (IQR: 35-114). Of 8, 7 underwent carotid endarterectomy with histopathological confirmation of recanalization. Of the 153 patients, 45 (29%) had further neurological events, and 38 (25%) were within the territory of the occluded ICA. In all, 76 patients died, and of the 53 with a confirmed cause of death, 12 (23%) were attributed to a cerebrovascular accident corresponding to the territory of the occluded artery.CONCLUSION: Recanalization of ICA occlusion is common and leads to significant neurological events. Duplex ultrasound follow-up appears mandatory.",

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author = "G Morris-Stiff and M Teli and Khan, {P Y} and Ogunbiyi, {S O} and Champ, {C S} and R Hibberd and R Brown and Bailey, {D M} and Winter, {R K} and Lewis, {M H}",

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TY - JOUR

T1 - Internal carotid artery occlusion

T2 - its natural history including recanalization and subsequent neurological events

AU - Morris-Stiff, G

AU - Teli, M

AU - Khan, P Y

AU - Ogunbiyi, S O

AU - Champ, C S

AU - Hibberd, R

AU - Brown, R

AU - Bailey, D M

AU - Winter, R K

AU - Lewis, M H

PY - 2013/11

Y1 - 2013/11

N2 - OBJECTIVE: To determine the incidence of recanalization of the occluded internal carotid artery (ICA) and establish its natural history.METHODS: Patients with duplex-confirmed ICA occlusions were identified, and a subgroup offered repeat scanning. The antemortem condition and cause of death of patients who died were recorded.RESULTS: Of 153 patients identified, 77 underwent follow-up at a median of 35 months (interquartile range [IQR]: 14-61).In all, 8 (10.3%) demonstrated recanalization at a median of 53 months (IQR: 35-114). Of 8, 7 underwent carotid endarterectomy with histopathological confirmation of recanalization. Of the 153 patients, 45 (29%) had further neurological events, and 38 (25%) were within the territory of the occluded ICA. In all, 76 patients died, and of the 53 with a confirmed cause of death, 12 (23%) were attributed to a cerebrovascular accident corresponding to the territory of the occluded artery.CONCLUSION: Recanalization of ICA occlusion is common and leads to significant neurological events. Duplex ultrasound follow-up appears mandatory.

AB - OBJECTIVE: To determine the incidence of recanalization of the occluded internal carotid artery (ICA) and establish its natural history.METHODS: Patients with duplex-confirmed ICA occlusions were identified, and a subgroup offered repeat scanning. The antemortem condition and cause of death of patients who died were recorded.RESULTS: Of 153 patients identified, 77 underwent follow-up at a median of 35 months (interquartile range [IQR]: 14-61).In all, 8 (10.3%) demonstrated recanalization at a median of 53 months (IQR: 35-114). Of 8, 7 underwent carotid endarterectomy with histopathological confirmation of recanalization. Of the 153 patients, 45 (29%) had further neurological events, and 38 (25%) were within the territory of the occluded ICA. In all, 76 patients died, and of the 53 with a confirmed cause of death, 12 (23%) were attributed to a cerebrovascular accident corresponding to the territory of the occluded artery.CONCLUSION: Recanalization of ICA occlusion is common and leads to significant neurological events. Duplex ultrasound follow-up appears mandatory.

KW - Aged

KW - Carotid Artery, Internal

KW - Carotid Stenosis

KW - Cause of Death

KW - Cerebrovascular Disorders

KW - Chronic Disease

KW - Endarterectomy, Carotid

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Predictive Value of Tests

KW - Recurrence

KW - Risk Factors

KW - Time Factors

KW - Treatment Outcome

KW - Ultrasonography, Doppler, Color

U2 - 10.1177/1538574413500539

DO - 10.1177/1538574413500539

M3 - Article

C2 - 24129794

SN - 1538-5744

VL - 47

SP - 603

EP - 607

JO - Vascular and endovascular surgery

JF - Vascular and endovascular surgery

IS - 8

ER -

Internal carotid artery occlusion: its natural history including recanalization and subsequent neurological events

Abstract

Keywords

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