Internal carotid artery occlusion: its natural history including recanalization and subsequent neurological events

G Morris-Stiff, M Teli, P Y Khan, S O Ogunbiyi, C S Champ, R Hibberd, R Brown, D M Bailey, R K Winter, M H Lewis

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE: To determine the incidence of recanalization of the occluded internal carotid artery (ICA) and establish its natural history.

METHODS: Patients with duplex-confirmed ICA occlusions were identified, and a subgroup offered repeat scanning. The antemortem condition and cause of death of patients who died were recorded.

RESULTS: Of 153 patients identified, 77 underwent follow-up at a median of 35 months (interquartile range [IQR]: 14-61).In all, 8 (10.3%) demonstrated recanalization at a median of 53 months (IQR: 35-114). Of 8, 7 underwent carotid endarterectomy with histopathological confirmation of recanalization. Of the 153 patients, 45 (29%) had further neurological events, and 38 (25%) were within the territory of the occluded ICA. In all, 76 patients died, and of the 53 with a confirmed cause of death, 12 (23%) were attributed to a cerebrovascular accident corresponding to the territory of the occluded artery.

CONCLUSION: Recanalization of ICA occlusion is common and leads to significant neurological events. Duplex ultrasound follow-up appears mandatory.

Original languageEnglish
Pages (from-to)603-7
Number of pages5
JournalVascular and endovascular surgery
Volume47
Issue number8
DOIs
Publication statusPublished - Nov 2013

Keywords

  • Aged
  • Carotid Artery, Internal
  • Carotid Stenosis
  • Cause of Death
  • Cerebrovascular Disorders
  • Chronic Disease
  • Endarterectomy, Carotid
  • Female
  • Humans
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Recurrence
  • Risk Factors
  • Time Factors
  • Treatment Outcome
  • Ultrasonography, Doppler, Color

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