Influence of retinoblastoma-related gene silencingon the initiation of DNA replication by African cassava mosaic virus Rep in cells of mature leaves in Nicotiana bethamiana plants.

Gareth Bruce; Mei Gu; Nongnong Shi; Yule Liu; Yiguo Hong

doi:10.1186/1743-422X-8-561

Influence of retinoblastoma-related gene silencingon the initiation of DNA replication by African cassava mosaic virus Rep in cells of mature leaves in Nicotiana bethamiana plants.

Gareth Bruce, Mei Gu, Nongnong Shi, Yule Liu, Yiguo Hong

Research output: Contribution to journal › Article › peer-review

Abstract

Geminiviruses mainly infect terminally differentiated tissues and cells in plants. They need to re-programme host cellular machinery for DNA replication. This process is thought to be mediated by inactivation of cell-cycle repressor proteins and by induction of host DNA synthesis protein expression through actions of the geminviral replication initiator protein (Rep).

Original language	English
Journal	Virology Journal
Volume	8
DOIs	https://doi.org/10.1186/1743-422X-8-561
Publication status	E-pub ahead of print - 28 Dec 2011
Externally published	Yes

Keywords

african cassava mosaic virus (acmv)
dna replication
replication initiator protein (rep)
retinoblastoma-related protein (rbr)
proliferating cell nuclear antigen (pcna)
virus-induced rna silencing (vigs)

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10.1186/1743-422X-8-561

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title = "Influence of retinoblastoma-related gene silencingon the initiation of DNA replication by African cassava mosaic virus Rep in cells of mature leaves in Nicotiana bethamiana plants.",

abstract = "Geminiviruses mainly infect terminally differentiated tissues and cells in plants. They need to re-programme host cellular machinery for DNA replication. This process is thought to be mediated by inactivation of cell-cycle repressor proteins and by induction of host DNA synthesis protein expression through actions of the geminviral replication initiator protein (Rep).",

keywords = "african cassava mosaic virus (acmv), dna replication, replication initiator protein (rep), retinoblastoma-related protein (rbr), proliferating cell nuclear antigen (pcna), virus-induced rna silencing (vigs)",

author = "Gareth Bruce and Mei Gu and Nongnong Shi and Yule Liu and Yiguo Hong",

year = "2011",

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doi = "10.1186/1743-422X-8-561",

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AU - Bruce, Gareth

AU - Gu, Mei

AU - Shi, Nongnong

AU - Liu, Yule

AU - Hong, Yiguo

PY - 2011/12/28

Y1 - 2011/12/28

N2 - Geminiviruses mainly infect terminally differentiated tissues and cells in plants. They need to re-programme host cellular machinery for DNA replication. This process is thought to be mediated by inactivation of cell-cycle repressor proteins and by induction of host DNA synthesis protein expression through actions of the geminviral replication initiator protein (Rep).

AB - Geminiviruses mainly infect terminally differentiated tissues and cells in plants. They need to re-programme host cellular machinery for DNA replication. This process is thought to be mediated by inactivation of cell-cycle repressor proteins and by induction of host DNA synthesis protein expression through actions of the geminviral replication initiator protein (Rep).

KW - african cassava mosaic virus (acmv)

KW - dna replication

KW - replication initiator protein (rep)

KW - retinoblastoma-related protein (rbr)

KW - proliferating cell nuclear antigen (pcna)

KW - virus-induced rna silencing (vigs)

U2 - 10.1186/1743-422X-8-561

DO - 10.1186/1743-422X-8-561

M3 - Article

C2 - 22204717

SN - 1743-422X

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JO - Virology Journal

JF - Virology Journal

ER -

Influence of retinoblastoma-related gene silencingon the initiation of DNA replication by African cassava mosaic virus Rep in cells of mature leaves in Nicotiana bethamiana plants.

Abstract

Keywords

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