Geminiviruses mainly infect terminally differentiated tissues and cells in plants. They need to re-programme host cellular machinery for DNA replication. This process is thought to be mediated by inactivation of cell-cycle repressor proteins and by induction of host DNA synthesis protein expression through actions of the geminviral replication initiator protein (Rep).
- african cassava mosaic virus (acmv)
- dna replication
- replication initiator protein (rep)
- retinoblastoma-related protein (rbr)
- proliferating cell nuclear antigen (pcna)
- virus-induced rna silencing (vigs)