Desymmetrization of diols by a tandem oxidation/Wittig olefination reaction

David J. Phillips; Kathryn S. Pillinger; Wei Li; Angela E. Taylor; Andrew E. Graham

doi:10.1039/b602329k

Desymmetrization of diols by a tandem oxidation/Wittig olefination reaction

David J. Phillips, Kathryn S. Pillinger, Wei Li, Angela E. Taylor, Andrew E. Graham^*

^*Corresponding author for this work

Faculty of Computing, Engineering and Science

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

Diols are desymmetrized by a tandem oxidation/Wittig olefination to give α,β-unsaturated hydroxy esters without the requirement for protecting group strategies; the α,β-unsaturated hydroxy esters are transformed into dienyl diesters using a second oxidation/Wittig olefination sequence using PCC.

Original language	English
Pages (from-to)	2280-2282
Number of pages	3
Journal	Chemical Communications
Issue number	21
DOIs	https://doi.org/10.1039/b602329k
Publication status	Published - 2006

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title = "Desymmetrization of diols by a tandem oxidation/Wittig olefination reaction",

abstract = "Diols are desymmetrized by a tandem oxidation/Wittig olefination to give α,β-unsaturated hydroxy esters without the requirement for protecting group strategies; the α,β-unsaturated hydroxy esters are transformed into dienyl diesters using a second oxidation/Wittig olefination sequence using PCC. ",

author = "Phillips, {David J.} and Pillinger, {Kathryn S.} and Wei Li and Taylor, {Angela E.} and Graham, {Andrew E.}",

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doi = "10.1039/b602329k",

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journal = "Chemical Communications",

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AU - Pillinger, Kathryn S.

AU - Li, Wei

AU - Taylor, Angela E.

AU - Graham, Andrew E.

PY - 2006

Y1 - 2006

N2 - Diols are desymmetrized by a tandem oxidation/Wittig olefination to give α,β-unsaturated hydroxy esters without the requirement for protecting group strategies; the α,β-unsaturated hydroxy esters are transformed into dienyl diesters using a second oxidation/Wittig olefination sequence using PCC.

AB - Diols are desymmetrized by a tandem oxidation/Wittig olefination to give α,β-unsaturated hydroxy esters without the requirement for protecting group strategies; the α,β-unsaturated hydroxy esters are transformed into dienyl diesters using a second oxidation/Wittig olefination sequence using PCC.

U2 - 10.1039/b602329k

DO - 10.1039/b602329k

M3 - Article

C2 - 16718329

AN - SCOPUS:33744500216

SN - 1359-7345

SP - 2280

EP - 2282

JO - Chemical Communications

JF - Chemical Communications

IS - 21

ER -

Desymmetrization of diols by a tandem oxidation/Wittig olefination reaction

Abstract

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