Abstract
In many magnetic resonance imaging (MRI) applications, it is necessary to compare regions of interest (ROIs) on different images of the same patient. This comparison is often made difficult when the scanned tissue volume is not in exactly the same three-dimensional location every time. Registration, the accurate alignment of the images through the determination of a transformation from one image space to another, is necessary so that ROIs may be compared correctly.
This paper outlines a new application of registration in the monitoring of rheumatic disease in the proximal interphalangeal joint [1] conducted at the University Hospital of Wales. In particular, registration is required for quantitative comparison of monomodal, serially-acquired images to increase the precision of treatment monitoring. These images correspond to the tissue content of a slice of given thickness of the joint.
We bring to light a number of complications which make identifying suitable transformations to achieve registration difficult. These complications preclude the straightforward application of a standard registration technique and require the development of a bespoke approach. In particular, this paper will show that 2D pixel-based registration is not appropriate for this application. It will go on to examine the factors of this problem which complicate registration
and will suggest how suitable transformations may be determined. Characteristics of such transformations will be shown.
This paper outlines a new application of registration in the monitoring of rheumatic disease in the proximal interphalangeal joint [1] conducted at the University Hospital of Wales. In particular, registration is required for quantitative comparison of monomodal, serially-acquired images to increase the precision of treatment monitoring. These images correspond to the tissue content of a slice of given thickness of the joint.
We bring to light a number of complications which make identifying suitable transformations to achieve registration difficult. These complications preclude the straightforward application of a standard registration technique and require the development of a bespoke approach. In particular, this paper will show that 2D pixel-based registration is not appropriate for this application. It will go on to examine the factors of this problem which complicate registration
and will suggest how suitable transformations may be determined. Characteristics of such transformations will be shown.
| Original language | English |
|---|---|
| Title of host publication | Image Processing II: Mathematical Methods, Algorithms and Applications |
| Editors | Jonathan M Blackledge, Martin J Turner |
| Publisher | IMA - Institute of Mathematics & its Applications |
| Pages | 115-132 |
| ISBN (Print) | 9781898563617 |
| Publication status | Published - 2000 |