TY - JOUR
T1 - Computational analyses of miRNAs from transcriptome of anti-malarial plant -Artemisia annua.
AU - Tatarinova, Tatiana
AU - Pérez-Quintero, Álvaro L
AU - Sablok, Gaurav
AU - Ahmad, Touqeer
AU - Conesa, Ana
AU - López, Camilo
PY - 2011/12/31
Y1 - 2011/12/31
N2 - We predicted and analyzed miRNAs precursors and targets using transcriptome of sweet wormwood (Artemisia annua L.), which is a source of an anti-malarial agent artemisinin. Among predicted miRNA targets, 29 (57%) correspond to unknown proteins, 5 (10%) to SQUAMOSA promoter-binding protein, 3 (6%) to Transport Inhibitor Response 1 protein; all other categories comprise the remaining 27% of the sequences. These targets are involved in response to copper deficiency, involved in copper homeostasis, mediating Aux/IAA proteins proteasomal degradation and auxin-regulated transcription. Repression of auxin signaling restricts growth of bacteria P. syringae, suggesting importance of miRNA-mediated suppression of auxin signaling in bacterial resistance.
AB - We predicted and analyzed miRNAs precursors and targets using transcriptome of sweet wormwood (Artemisia annua L.), which is a source of an anti-malarial agent artemisinin. Among predicted miRNA targets, 29 (57%) correspond to unknown proteins, 5 (10%) to SQUAMOSA promoter-binding protein, 3 (6%) to Transport Inhibitor Response 1 protein; all other categories comprise the remaining 27% of the sequences. These targets are involved in response to copper deficiency, involved in copper homeostasis, mediating Aux/IAA proteins proteasomal degradation and auxin-regulated transcription. Repression of auxin signaling restricts growth of bacteria P. syringae, suggesting importance of miRNA-mediated suppression of auxin signaling in bacterial resistance.
KW - mirna
KW - bioinformatics
M3 - Article
JO - Biotechnology Letters
JF - Biotechnology Letters
SN - 0141-5492
ER -