Barium manganate in microwave-assisted oxidation reactions: synthesis of lactones by oxidative cyclization of diols

Mark C. Bagley; Zhifan Lin; David J. Phillips; Andrew E. Graham

doi:10.1016/j.tetlet.2009.09.117

Barium manganate in microwave-assisted oxidation reactions: synthesis of lactones by oxidative cyclization of diols

Mark C. Bagley^*, Zhifan Lin, David J. Phillips, Andrew E. Graham

^*Corresponding author for this work

Faculty of Computing, Engineering and Science

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Microwave irradiation of a range of diols at 150 °C in acetonitrile in the presence of three equivalents of barium manganate facilitates a novel tandem oxidation/heterocyclocondensation to give the corresponding lactone, including both small and medium ring lactones, in only one hour and in high yield without the need for chromatographic purification.

Original language	English
Pages (from-to)	6823-6825
Number of pages	3
Journal	Tetrahedron Letters
Volume	50
Issue number	49
DOIs	https://doi.org/10.1016/j.tetlet.2009.09.117
Publication status	Published - 9 Dec 2009

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10.1016/j.tetlet.2009.09.117

22 Citations
1 Doctoral Thesis

Application of Tandem Oxidation Processes to the Synthesis of Novel Oxabicycloalkane Protein Phosphatase Inhibitors
Phillips, D., 2007
Research output: Types of Thesis › Doctoral Thesis

Cite this

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title = "Barium manganate in microwave-assisted oxidation reactions: synthesis of lactones by oxidative cyclization of diols",

abstract = "Microwave irradiation of a range of diols at 150 °C in acetonitrile in the presence of three equivalents of barium manganate facilitates a novel tandem oxidation/heterocyclocondensation to give the corresponding lactone, including both small and medium ring lactones, in only one hour and in high yield without the need for chromatographic purification.",

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T2 - synthesis of lactones by oxidative cyclization of diols

AU - Bagley, Mark C.

AU - Lin, Zhifan

AU - Phillips, David J.

AU - Graham, Andrew E.

PY - 2009/12/9

Y1 - 2009/12/9

N2 - Microwave irradiation of a range of diols at 150 °C in acetonitrile in the presence of three equivalents of barium manganate facilitates a novel tandem oxidation/heterocyclocondensation to give the corresponding lactone, including both small and medium ring lactones, in only one hour and in high yield without the need for chromatographic purification.

AB - Microwave irradiation of a range of diols at 150 °C in acetonitrile in the presence of three equivalents of barium manganate facilitates a novel tandem oxidation/heterocyclocondensation to give the corresponding lactone, including both small and medium ring lactones, in only one hour and in high yield without the need for chromatographic purification.

U2 - 10.1016/j.tetlet.2009.09.117

DO - 10.1016/j.tetlet.2009.09.117

M3 - Article

AN - SCOPUS:70350007181

SN - 1873-3581

VL - 50

SP - 6823

EP - 6825

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 49

ER -

Barium manganate in microwave-assisted oxidation reactions: synthesis of lactones by oxidative cyclization of diols

Abstract

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Research output

Application of Tandem Oxidation Processes to the Synthesis of Novel Oxabicycloalkane Protein Phosphatase Inhibitors

Cite this