TY - GEN
T1 - Alzheimer's Disease Prediction using Advanced Predictive Intelligence Model
AU - Panda, Ayush
AU - Suman, Ayush
AU - Mishra, Nilamadhab
AU - Yang, Tiansheng
AU - Rathore, Bharati
AU - Mo, Danyu
AU - Wang, Lu
PY - 2024/10/24
Y1 - 2024/10/24
N2 - Alzheimer's disease (AD), a neurodegenerative disorder that progresses over time, disrupts cognitive functions, ultimately resulting in severe dementia. The pathological hallmark of Alzheimer's disease is predominantly characterized by the presence of amyloid plaques and neurofibrillary tangles, with biomarkers essential for diagnosis. Traditional biomarkers, such as MRI, PET scans, and CSF measures, though effective, often detect the disease only at later stages and face challenges of high cost and limited accessibility. This study explores the potential of machine learning (ML) and deep learning (DL) methods in predicting early-stage Alzheimer's disease (AD) by analyzing intricate datasets, such as genetic information, cerebrospinal fluid (CSF) biomarkers, neuroimaging data, and electronic health records (EHRs). The proposed model integrates various data types to enhance prediction accuracy and timeliness, allowing for early intervention strategies. With the rising prevalence of AD and its significant impact on individuals and society, innovative approaches leveraging ML and DL can improve diagnostic processes and patient outcomes. This research highlights the integration of advanced computational methods with conventional biomarkers, offering a comprehensive approach to AD prediction and management.
AB - Alzheimer's disease (AD), a neurodegenerative disorder that progresses over time, disrupts cognitive functions, ultimately resulting in severe dementia. The pathological hallmark of Alzheimer's disease is predominantly characterized by the presence of amyloid plaques and neurofibrillary tangles, with biomarkers essential for diagnosis. Traditional biomarkers, such as MRI, PET scans, and CSF measures, though effective, often detect the disease only at later stages and face challenges of high cost and limited accessibility. This study explores the potential of machine learning (ML) and deep learning (DL) methods in predicting early-stage Alzheimer's disease (AD) by analyzing intricate datasets, such as genetic information, cerebrospinal fluid (CSF) biomarkers, neuroimaging data, and electronic health records (EHRs). The proposed model integrates various data types to enhance prediction accuracy and timeliness, allowing for early intervention strategies. With the rising prevalence of AD and its significant impact on individuals and society, innovative approaches leveraging ML and DL can improve diagnostic processes and patient outcomes. This research highlights the integration of advanced computational methods with conventional biomarkers, offering a comprehensive approach to AD prediction and management.
KW - predictive intelligence
KW - early-stage diagnosis
KW - biomarkers
KW - neuroimaging
KW - neurodegenerative disorders
KW - Accuracy
KW - Computational modeling
KW - Biological system modeling
KW - Soft sensors
KW - Training data
KW - Predictive models
KW - Prediction algorithms
KW - Data models
KW - Alzheimer's disease
U2 - 10.1109/iacis61494.2024.10721920
DO - 10.1109/iacis61494.2024.10721920
M3 - Conference contribution
SN - 979-8-3503-6067-7
T3 - 2024 International Conference on Intelligent Algorithms for Computational Intelligence Systems (IACIS)
BT - Edit 2024 International Conference on Intelligent Algorithms for Computational Intelligence Systems (IACIS)
PB - Institute of Electrical and Electronics Engineers
T2 - International Conference on Intelligent Algorithms for Computational Intelligence Systems
Y2 - 23 August 2024 through 24 August 2024
ER -