A Preparative and Solution Study of a Modified β-Cyclodextrin and its Europium(III) Complex, and their Interactions with Racemic Amino Acid Anions

Suzanna D. Kean, Christopher J. Easton, Stephen F. Lincoln*, David Parker

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

The synthesis and characterization of 6A-deoxy-6 A-(1,4,7-tri(carboxylatomethyl)-1,4,7,10-tetraazacyclododecan-10-yl)- β-cyclodextrin (1b) are reported. A fluorescence lifetime study of its Eu3+ complex (1c) is consistent with one water coordinating Eu3+ in addition to hepta-coordination by (1b). 1H NMR studies are consistent with (1b) forming host-guest complexes with (R/S)-histidinate (2a), (R/S)-tyrosinate (2b), (R/S)-phenylalaninate (2c), and (R/S)-tryptophanate (2d), with enantioselectivity shown for (2b). Similar studies are consistent with (1c) complexing (2a-d), with enantioselectivity shown for (2a).

Original languageEnglish
Pages (from-to)535-539
Number of pages5
JournalAustralian Journal of Chemistry
Volume54
Issue number8
DOIs
Publication statusPublished - 1 Dec 2001
Externally publishedYes

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