The additional costs of antibiotics and re-consultations for antibiotic-resistant Escherichia coli urinary tract infections managed in general practice

David Cohen, Fasihul Alam, Christopher Butler, Frank Dunstan, Zoe Roberts, Sharon Hillier, Stephen Palmer

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

Crynodeb

The emergence of antibiotic resistance is a major threat to public health. In the UK, most antibiotics are prescribed in general practice but the extra costs to general practice of resistant infections have not previously been well described. We compared the costs of treating patients presenting with resistant Escherichia coli urinary tract infections (UTIs) (resistant to ampicillin, trimethoprim or at least one antibiotic) with the costs of treating patients with UTIs that were sensitive to all six tested antibiotics (ampicillin, trimethoprim, anoxicillin/clavulanic acid, cefalexin, ciprofloxacin and nitrofurantoin) with regard to reconsultations and antibiotics prescribed. There were significantly higher antibiotics costs (mean extra antibiotic cost £1.19 / Euro 1.75), re-consultation costs (£2.42 / Euro 3.55) and total costs (£3.62 / Euro 5.31) for patients whose infections were resistant to at least one antibiotic compared with those with sensitive infections even after accounting for potentially confounding factors. Although these per-patient costs may appear small, they do not take into account the full additional costs of resistant UTIs in the community and, given the high prevalence of UTIs, the overall costs to the health service are substantial.
Iaith wreiddiolSaesneg
Tudalennau (o-i)255 - 257
Nifer y tudalennau2
CyfnodolynInternational Journal of Antimicrobial Agents
Cyfrol33
Rhif cyhoeddi3
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 1 Ion 2009

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Gweld gwybodaeth am bynciau ymchwil 'The additional costs of antibiotics and re-consultations for antibiotic-resistant Escherichia coli urinary tract infections managed in general practice'. Gyda’i gilydd, maen nhw’n ffurfio ôl bys unigryw.

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