Sedentary aging increases resting and exercise-induced intramuscular free radical formation

Damian Bailey; Jane McEneny; Odile Mathieu-Costello; Robert R Henry; Philip E James; Joe M McCord; Sylvia Pietri; Ian S Young; Russell S Richardson

doi:10.1152/japplphysiol.00354.2010

Sedentary aging increases resting and exercise-induced intramuscular free radical formation

Damian Bailey, Jane McEneny, Odile Mathieu-Costello, Robert R Henry, Philip E James, Joe M McCord, Sylvia Pietri, Ian S Young, Russell S Richardson

Cyfadran y Gwyddorau Bywyd ac Addysg

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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Mitochondrial free radical formation has been implicated as a potential mechanism underlying degenerative senescence, although human data are lacking. Therefore, the present study was designed to examine if resting and exercise-induced intramuscular free radical-mediated lipid peroxidation is indeed increased across the spectrum of sedentary aging.

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	449 - 456
Nifer y tudalennau	7
Cyfnodolyn	Journal of Applied Physiology
Cyfrol	109
Rhif cyhoeddi	2
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1152/japplphysiol.00354.2010
Statws	Cyhoeddwyd - 27 Mai 2010

Mynediad at Ddogfen

10.1152/japplphysiol.00354.2010

Dyfynnu hyn

@article{6b2a7fd0c7fa475cbc2887fb259bd0d0,

title = "Sedentary aging increases resting and exercise-induced intramuscular free radical formation",

abstract = "Mitochondrial free radical formation has been implicated as a potential mechanism underlying degenerative senescence, although human data are lacking. Therefore, the present study was designed to examine if resting and exercise-induced intramuscular free radical-mediated lipid peroxidation is indeed increased across the spectrum of sedentary aging.",

keywords = "electron paramagnetic resonance spectroscopy, spin trapping, mitochondria, lipid peroxidation, free radical theory of aging",

author = "Damian Bailey and Jane McEneny and Odile Mathieu-Costello and Henry, {Robert R} and James, {Philip E} and McCord, {Joe M} and Sylvia Pietri and Young, {Ian S} and Richardson, {Russell S}",

year = "2010",

month = may,

day = "27",

doi = "10.1152/japplphysiol.00354.2010",

language = "English",

volume = "109",

pages = "449 -- 456",

journal = "Journal of Applied Physiology",

issn = "0161-7567",

publisher = "American Physiological Society",

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T1 - Sedentary aging increases resting and exercise-induced intramuscular free radical formation

AU - Bailey, Damian

AU - McEneny, Jane

AU - Mathieu-Costello, Odile

AU - Henry, Robert R

AU - James, Philip E

AU - McCord, Joe M

AU - Pietri, Sylvia

AU - Young, Ian S

AU - Richardson, Russell S

PY - 2010/5/27

Y1 - 2010/5/27

N2 - Mitochondrial free radical formation has been implicated as a potential mechanism underlying degenerative senescence, although human data are lacking. Therefore, the present study was designed to examine if resting and exercise-induced intramuscular free radical-mediated lipid peroxidation is indeed increased across the spectrum of sedentary aging.

AB - Mitochondrial free radical formation has been implicated as a potential mechanism underlying degenerative senescence, although human data are lacking. Therefore, the present study was designed to examine if resting and exercise-induced intramuscular free radical-mediated lipid peroxidation is indeed increased across the spectrum of sedentary aging.

KW - electron paramagnetic resonance spectroscopy

KW - spin trapping

KW - mitochondria

KW - lipid peroxidation

KW - free radical theory of aging

U2 - 10.1152/japplphysiol.00354.2010

DO - 10.1152/japplphysiol.00354.2010

M3 - Article

C2 - 20507973

SN - 0161-7567

VL - 109

SP - 449

EP - 456

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

IS - 2

ER -

Sedentary aging increases resting and exercise-induced intramuscular free radical formation

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Mynediad at Ddogfen

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