Nanoporous Aluminosilicate Mediated Synthesis of 2- and 2,2-substituted 2,3-Dihydroquinazolin-4(1H)-ones

Matthew Aldred, Fuxuan Li, Rong Kuang, Owen L. Thomas, Thomas Davies, Stuart H. Taylor, Peter Miedziak, Andrew Graham*

*Awdur cyfatebol y gwaith hwn

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

Crynodeb

Nanoporous silicate materials, made by an operationally simple evaporation-induced selfassembly (EISA) approach, efficiently catalyze the formation of 2-substituted 2,3-dihydroquinazolin4(1H)-ones from aldehydes and dimethyl acetals. This methodology can be extended to encompass the reaction of ketones and ketals to provide facile access to 2,2-disubstituted and spiro dihydroquinazolin4(1H)-ones in high yields and short reaction times.
Iaith wreiddiolSaesneg
Rhif yr erthygl155037
Nifer y tudalennau5
CyfnodolynTetrahedron Letters
Cyfrol140
Dyddiad ar-lein cynnar26 Maw 2024
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 29 Maw 2024

Ôl bys

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