Nanoporous Aluminosilicate-Catalyzed Telescoped Acetalization-Direct Aldol Reactions of Acetals with 1,3-Dicarbonyl Compounds

Thomas Edward Davies; Stuart Hamilton Taylor; Andrew Edward Graham

doi:10.1021/acsomega.8b02047

Nanoporous Aluminosilicate-Catalyzed Telescoped Acetalization-Direct Aldol Reactions of Acetals with 1,3-Dicarbonyl Compounds

Thomas Edward Davies, Stuart Hamilton Taylor, Andrew Edward Graham

Cyfadran Cyfrifiadureg, Peirianneg a Gwyddoniaeth

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

41 Wedi eu Llwytho i Lawr (Pure)

Crynodeb

Nanoporous aluminosilicate materials, synthesized by an evaporation-induced self-assembly process, catalyze the direct aldol reaction of acyclic acetals with a range of 1,3-dicarbonyl compounds to produce the corresponding aldol addition products in high yield, rather than the expected Knoevenagel elimination products. By carrying out the reaction in the presence of either dimethoxy propane or the corresponding orthoester, it is possible to capitalize on the ability of these aluminosilicate materials to catalyze the corresponding acetalization reaction leading to the development of novel telescoped, acetalization-direct aldol addition reaction protocols

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	15482-15491
Cyfnodolyn	ACS Omega
Cyfrol	3
Rhif cyhoeddi	11
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1021/acsomega.8b02047
Statws	Cyhoeddwyd - 30 Tach 2018

NDC y CU

Mae’r allbwn hwn yn cyfrannu at y Nod(au) Datblygu Cynaliadwy canlynol

Mynediad at Ddogfen

10.1021/acsomega.8b02047Trwydded: Arall

acsomega.8b02047Fersiwn derfynol wedi’i chyhoeddi, 1.01 MBTrwydded: Arall

Dyfynnu hyn

@article{0216a89c0cc64243aecbe345d293d30d,

title = "Nanoporous Aluminosilicate-Catalyzed Telescoped Acetalization-Direct Aldol Reactions of Acetals with 1,3-Dicarbonyl Compounds",

abstract = "Nanoporous aluminosilicate materials, synthesized by an evaporation-induced self-assembly process, catalyze the direct aldol reaction of acyclic acetals with a range of 1,3-dicarbonyl compounds to produce the corresponding aldol addition products in high yield, rather than the expected Knoevenagel elimination products. By carrying out the reaction in the presence of either dimethoxy propane or the corresponding orthoester, it is possible to capitalize on the ability of these aluminosilicate materials to catalyze the corresponding acetalization reaction leading to the development of novel telescoped, acetalization-direct aldol addition reaction protocols",

keywords = "Addition reaction, Catalysts, Nanoporous materials, Self-assembly",

author = "Davies, {Thomas Edward} and Taylor, {Stuart Hamilton} and Graham, {Andrew Edward}",

year = "2018",

month = nov,

day = "30",

doi = "10.1021/acsomega.8b02047",

language = "English",

volume = "3",

pages = "15482--15491",

journal = "ACS Omega",

issn = "2470-1343",

publisher = "American Chemical Society",

number = "11",

}

TY - JOUR

T1 - Nanoporous Aluminosilicate-Catalyzed Telescoped Acetalization-Direct Aldol Reactions of Acetals with 1,3-Dicarbonyl Compounds

AU - Davies, Thomas Edward

AU - Taylor, Stuart Hamilton

AU - Graham, Andrew Edward

PY - 2018/11/30

Y1 - 2018/11/30

N2 - Nanoporous aluminosilicate materials, synthesized by an evaporation-induced self-assembly process, catalyze the direct aldol reaction of acyclic acetals with a range of 1,3-dicarbonyl compounds to produce the corresponding aldol addition products in high yield, rather than the expected Knoevenagel elimination products. By carrying out the reaction in the presence of either dimethoxy propane or the corresponding orthoester, it is possible to capitalize on the ability of these aluminosilicate materials to catalyze the corresponding acetalization reaction leading to the development of novel telescoped, acetalization-direct aldol addition reaction protocols

AB - Nanoporous aluminosilicate materials, synthesized by an evaporation-induced self-assembly process, catalyze the direct aldol reaction of acyclic acetals with a range of 1,3-dicarbonyl compounds to produce the corresponding aldol addition products in high yield, rather than the expected Knoevenagel elimination products. By carrying out the reaction in the presence of either dimethoxy propane or the corresponding orthoester, it is possible to capitalize on the ability of these aluminosilicate materials to catalyze the corresponding acetalization reaction leading to the development of novel telescoped, acetalization-direct aldol addition reaction protocols

KW - Addition reaction

KW - Catalysts

KW - Nanoporous materials

KW - Self-assembly

U2 - 10.1021/acsomega.8b02047

DO - 10.1021/acsomega.8b02047

M3 - Article

SN - 2470-1343

VL - 3

SP - 15482

EP - 15491

JO - ACS Omega

JF - ACS Omega

IS - 11

ER -

Nanoporous Aluminosilicate-Catalyzed Telescoped Acetalization-Direct Aldol Reactions of Acetals with 1,3-Dicarbonyl Compounds

Crynodeb

NDC y CU

Mynediad at Ddogfen

Ôl bys

Dyfynnu hyn