Metal triflate catalysed acetal exchange reactions of glycerol under solvent-free conditions

Brendan M. Smith; Tomasz M. Kubczyk; Andrew E. Graham

doi:10.1039/c2ra20100c

Metal triflate catalysed acetal exchange reactions of glycerol under solvent-free conditions

Brendan M. Smith, Tomasz M. Kubczyk, Andrew E. Graham^*

^*Awdur cyfatebol y gwaith hwn

Cyfadran Cyfrifiadureg, Peirianneg a Gwyddoniaeth

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

11 Dyfyniadau (Scopus)

Crynodeb

Catalytic quantities of indium(iii) triflate (In(OTf) ₃) efficiently promote transacetalisation reactions of glycerol with acyclic acetals to generate the corresponding cyclic acetals under solvent-free reaction conditions. The protocol is rapid and employs very mild reaction conditions. Unreactive ketones, such as acetophenone or benzophenone, undergo efficient acetalisation in the presence of In(OTf) ₃ and trimethyl orthoformate (TMOF) to give high conversions of the corresponding glycerol acetals.

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	2702-2706
Nifer y tudalennau	5
Cyfnodolyn	RSC Advances
Cyfrol	2
Rhif cyhoeddi	7
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1039/c2ra20100c
Statws	Cyhoeddwyd - 7 Ebr 2012

Mynediad at Ddogfen

10.1039/c2ra20100cTrwydded: CC BY-NC-ND

11 Dyfyniadau
1 Thesis Doethurol

The Utilisation of Indium(III) Salts as Highly Efficient Catalysts in Organic Synthesis
Smith, B., 2008
Allbwn ymchwil: Mathau o Thesis › Thesis Doethurol

Dyfynnu hyn

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title = "Metal triflate catalysed acetal exchange reactions of glycerol under solvent-free conditions",

abstract = "Catalytic quantities of indium(iii) triflate (In(OTf) 3) efficiently promote transacetalisation reactions of glycerol with acyclic acetals to generate the corresponding cyclic acetals under solvent-free reaction conditions. The protocol is rapid and employs very mild reaction conditions. Unreactive ketones, such as acetophenone or benzophenone, undergo efficient acetalisation in the presence of In(OTf) 3 and trimethyl orthoformate (TMOF) to give high conversions of the corresponding glycerol acetals. ",

author = "Smith, {Brendan M.} and Kubczyk, {Tomasz M.} and Graham, {Andrew E.}",

year = "2012",

month = apr,

day = "7",

doi = "10.1039/c2ra20100c",

language = "English",

volume = "2",

pages = "2702--2706",

journal = "RSC Advances",

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publisher = "Royal Society of Chemistry",

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T1 - Metal triflate catalysed acetal exchange reactions of glycerol under solvent-free conditions

AU - Smith, Brendan M.

AU - Kubczyk, Tomasz M.

AU - Graham, Andrew E.

PY - 2012/4/7

Y1 - 2012/4/7

N2 - Catalytic quantities of indium(iii) triflate (In(OTf) 3) efficiently promote transacetalisation reactions of glycerol with acyclic acetals to generate the corresponding cyclic acetals under solvent-free reaction conditions. The protocol is rapid and employs very mild reaction conditions. Unreactive ketones, such as acetophenone or benzophenone, undergo efficient acetalisation in the presence of In(OTf) 3 and trimethyl orthoformate (TMOF) to give high conversions of the corresponding glycerol acetals.

AB - Catalytic quantities of indium(iii) triflate (In(OTf) 3) efficiently promote transacetalisation reactions of glycerol with acyclic acetals to generate the corresponding cyclic acetals under solvent-free reaction conditions. The protocol is rapid and employs very mild reaction conditions. Unreactive ketones, such as acetophenone or benzophenone, undergo efficient acetalisation in the presence of In(OTf) 3 and trimethyl orthoformate (TMOF) to give high conversions of the corresponding glycerol acetals.

U2 - 10.1039/c2ra20100c

DO - 10.1039/c2ra20100c

M3 - Article

AN - SCOPUS:84859127486

SN - 2046-2069

VL - 2

SP - 2702

EP - 2706

JO - RSC Advances

JF - RSC Advances

IS - 7

ER -

Metal triflate catalysed acetal exchange reactions of glycerol under solvent-free conditions

Crynodeb

Mynediad at Ddogfen

Ôl bys

Allbwn Ymchwil

The Utilisation of Indium(III) Salts as Highly Efficient Catalysts in Organic Synthesis

Dyfynnu hyn