Long-term Survival and Reintervention Following Thoracic Endovascular Aortic Repair in Blunt Traumatic Thoracic Aortic Injury: A Systematic Review and Meta-analysis

Matti Jubouri, Abdelaziz O Surkhi, Mohammed Al-Tawil, Alexander Geragotellis, Tareq Z I Abdaljawwad, Mohanad Qudaih, Mohammed I R Elrayes, Madlen Dewi, Thurkga Moothathamby, Aya Hammad, Idhrees Mohammed, Wael I Awad, Mario D'Oria, Gabriele Piffaretti, Damian M Bailey, Ian M Williams, Mohamad Bashir*

*Awdur cyfatebol y gwaith hwn

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygl adolyguadolygiad gan gymheiriaid

Crynodeb

Background: Blunt thoracic aortic injury (BTAI) represents one of the most devastating scenarios of vascular trauma. Different management strategies are available with varying clinical outcomes. However, thoracic endovascular aortic repair (TEVAR) has become the first-line option for most BTAI patients, mainly owing to its minimally invasive nature, yielding improved immediate results. This meta-analysis aims to investigate mortality, long-term survival, and reintervention following TEVAR in BTAI. Material and Methods: A systematic review conducted a comprehensive literature search on multiple electronic databases using strict search terms. Twenty-seven studies met the set inclusion/exclusion criteria. A proportional meta-analysis of extracted data was conducted using the Comprehensive Meta-Analysis Software, v.4. Results: 1498 BTAI patients who underwent TEVAR were included. Using the SVS grading system, 2.6% of the population had Grade 1 injuries, 13.6% Grade 2, 62.2% Grade 3, 19.6% Grade 4, and 1.9% unspecific. All-cause mortality did not exceed 20% in all studies except one outlier with a 37% mortality rate. Using the random effects model, the pooled estimate of overall mortality was 12% (95% confidence interval [CI], 5.35–8.55%; I 2 = 70.6%). This was 91% (95% CI, 88.6–93.2; I 2 = 30.2%) at 6 months, 90.1% (95% CI, 86.7–92.3; I 2 = 53.6%) at 1 year, 89.2% (95% CI, 85.2–91.8; I2 = 62.3%) at 2 years, and 88.1% (95% CI, 83.3–90.9; I 2 = 69.6%) at 5 years. Moreover, the pooled estimate of reintervention was 6.4% (95% CI, 0.1–0.49%; I 2 = 81.7%). Conclusions: Despite the high morbidity and mortality associated with BTAI, TEVAR has proven to be a safe and effective management strategy with favorable long-term survival and minimal need for reintervention. Nevertheless, diagnosis of BTAI requires a high index of suspicion with appropriate grading and prompt transfer to trauma centers with appropriate TEVAR facilities.

Iaith wreiddiolSaesneg
Tudalennau (o-i)162-176
Nifer y tudalennau15
CyfnodolynAnnals of Vascular Surgery
Cyfrol109
Rhif cyhoeddi00
Dyddiad ar-lein cynnar14 Gorff 2024
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 9 Awst 2024

Dyfynnu hyn