Crynodeb
Acyclic acetals and ketals undergo transacetalisation in the presence of catalytic quantities of indium(III) triflate (In(OTf) 3) and diols or triols under solvent-free conditions to generate the corresponding cyclic acetals and ketals in excellent yield. The methodology has been further developed to encompass a tandem acetalisation-acetal exchange protocol, which provides a facile and high yielding route to cyclic ketals from unreactive ketones under very mild reaction conditions.
Iaith wreiddiol | Saesneg |
---|---|
Tudalennau (o-i) | 7775-7781 |
Nifer y tudalennau | 7 |
Cyfnodolyn | Tetrahedron Letters |
Cyfrol | 68 |
Rhif cyhoeddi | 38 |
Dynodwyr Gwrthrych Digidol (DOIs) | |
Statws | Cyhoeddwyd - 23 Medi 2012 |