Genomic Assemblies of Members of Burkholderia and Related Genera as a Resource for Natural Product Discovery

Alex J. Mullins, Cerith Jones, Matthew J. Bull, Gordon Webster, Julian Parkhill, Thomas R. Connor, James A. H. Murray, Gregory L. Challis, Eshwar Mahenthiralingam

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

66 Wedi eu Llwytho i Lawr (Pure)

Crynodeb

The genomes of 450 members of Burkholderiaceae, isolated from clinical and environmental sources, were sequenced and assembled as a resource for genome mining. Genomic analysis of the collection has enabled the identification of multiple metabolites and their biosynthetic gene clusters, including the antibiotics gladiolin, icosalide A, enacyloxin, and cepacin A.
Iaith wreiddiolSaesneg
Rhif yr erthygle00485
Nifer y tudalennau17
CyfnodolynMicrobiology Resource Announcements
Cyfrol9
Rhif cyhoeddi42
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 15 Hyd 2020

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