Efficient oxidation-Wittig olefination-Diels-Alder multicomponent reactions of α-hydroxyketones

Geraint H. Harris; Andrew E. Graham

doi:10.1016/j.tetlet.2010.10.121

Efficient oxidation-Wittig olefination-Diels-Alder multicomponent reactions of α-hydroxyketones

Geraint H. Harris, Andrew E. Graham

Cyfadran Cyfrifiadureg, Peirianneg a Gwyddoniaeth

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

16 Dyfyniadau (Scopus)

Crynodeb

α-Hydroxyketones undergo efficient tandem oxidation-Wittig olefination reactions in the presence of an oxidant to produce high yields of γ-ketocrotonate products. On carrying out the oxidation-Wittig olefination reaction in the presence of 2,3-dimethyl-1,3-butadiene, a novel multicomponent reaction sequence provides access to cycloadducts in high yield.

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	6890-6892
Nifer y tudalennau	3
Cyfnodolyn	Tetrahedron Letters
Cyfrol	51
Rhif cyhoeddi	52
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1016/j.tetlet.2010.10.121
Statws	Cyhoeddwyd - 29 Rhag 2010

Mynediad at Ddogfen

10.1016/j.tetlet.2010.10.121Trwydded: CC BY-NC-ND

Dyfynnu hyn

@article{99ecf0c9f344440ebb36dfebe76c2db0,

title = "Efficient oxidation-Wittig olefination-Diels-Alder multicomponent reactions of α-hydroxyketones",

abstract = "α-Hydroxyketones undergo efficient tandem oxidation-Wittig olefination reactions in the presence of an oxidant to produce high yields of γ-ketocrotonate products. On carrying out the oxidation-Wittig olefination reaction in the presence of 2,3-dimethyl-1,3-butadiene, a novel multicomponent reaction sequence provides access to cycloadducts in high yield. ",

author = "Harris, {Geraint H.} and Graham, {Andrew E.}",

year = "2010",

month = dec,

day = "29",

doi = "10.1016/j.tetlet.2010.10.121",

language = "English",

volume = "51",

pages = "6890--6892",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier",

number = "52",

}

TY - JOUR

T1 - Efficient oxidation-Wittig olefination-Diels-Alder multicomponent reactions of α-hydroxyketones

AU - Harris, Geraint H.

AU - Graham, Andrew E.

PY - 2010/12/29

Y1 - 2010/12/29

N2 - α-Hydroxyketones undergo efficient tandem oxidation-Wittig olefination reactions in the presence of an oxidant to produce high yields of γ-ketocrotonate products. On carrying out the oxidation-Wittig olefination reaction in the presence of 2,3-dimethyl-1,3-butadiene, a novel multicomponent reaction sequence provides access to cycloadducts in high yield.

AB - α-Hydroxyketones undergo efficient tandem oxidation-Wittig olefination reactions in the presence of an oxidant to produce high yields of γ-ketocrotonate products. On carrying out the oxidation-Wittig olefination reaction in the presence of 2,3-dimethyl-1,3-butadiene, a novel multicomponent reaction sequence provides access to cycloadducts in high yield.

U2 - 10.1016/j.tetlet.2010.10.121

DO - 10.1016/j.tetlet.2010.10.121

M3 - Article

AN - SCOPUS:78650677199

SN - 0040-4039

VL - 51

SP - 6890

EP - 6892

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 52

ER -

Efficient oxidation-Wittig olefination-Diels-Alder multicomponent reactions of α-hydroxyketones

Crynodeb

Mynediad at Ddogfen

Ôl bys

Dyfynnu hyn