An exploratory analysis of spatial variations in organ donation registration rates in Wales prior to the implementation of the Human Transplantation (Wales) Act 2013

Spatial variations in rates of registered organ donors have not been studied in the UK at detailed spatial scales despite some evidence of national and regional differences. By drawing on the findings from the existing literature, this study examines associations between small-area variations in rates of new registrants to the UK organ donor register (ODR) within Wales and key demographic factors. Using map-based visualisations and statistical regression methods, spatial patterns in new registrants to the ODR are identified within Wales, a country which moved to an opt-out system of consent for organ donation following the Human Transplantation (Wales) Act 2013. By identifying the underlying factors associated with trends in rates of new ODR sign-up, this study aims to highlight the types of approaches that could be used to help to inform future targeted interventions aimed at improving registration rates.