A bis(η5-cyclopentadienyl)cobalt complex of a bis-dithiolene: a chemical analogue of the metal centres of the DMSO reductase family of molybdenum and tungsten enzymes, in particular ferredoxin aldehyde oxidoreductase

France-Aimée  Alphonse; Rehana Karim; Céline  Cano-Soumillac; Marielle Hebray; David Collison; David Garner; John Joule

doi:10.1016/j.tet.2005.08.095

A bis(η5-cyclopentadienyl)cobalt complex of a bis-dithiolene: a chemical analogue of the metal centres of the DMSO reductase family of molybdenum and tungsten enzymes, in particular ferredoxin aldehyde oxidoreductase

France-Aimée Alphonse, Rehana Karim, Céline Cano-Soumillac, Marielle Hebray, David Collison, David Garner, John Joule

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

Crynodeb

The synthesis is described of a bis-ene-1,2-dithiolate pro-ligand, designed to model the stereochemical situation in the cofactor of the tungsten enzyme ferredoxin aldehyde oxidoreductase from Pyrococcus furiosus. Each masked ene-1,2-dithiolate unit is mounted on a pyrano[2,3-b]tetrahydroquinoxaline tricycle, comparable to the pyrano[2,3-g]tetrahydropteridines found in all molybdoenzymes and tungsten analogues. Hydrolytic release of the bis-ligand was confirmed by its entrapment as a double (η5-C5H5)Co complex.

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	11010-11019
Nifer y tudalennau	10
Cyfnodolyn	Tetrahedron Letters
Cyfrol	61
Rhif cyhoeddi	46
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1016/j.tet.2005.08.095
Statws	Cyhoeddwyd - 2005

Mynediad at Ddogfen

10.1016/j.tet.2005.08.095Trwydded: Amhenodol

Ôl bys

Gweld gwybodaeth am bynciau ymchwil 'A bis(η5-cyclopentadienyl)cobalt complex of a bis-dithiolene: a chemical analogue of the metal centres of the DMSO reductase family of molybdenum and tungsten enzymes, in particular ferredoxin aldehyde oxidoreductase'. Gyda’i gilydd, maen nhw’n ffurfio ôl bys unigryw.

Dyfynnu hyn

Alphonse, F-A., Karim, R., Cano-Soumillac, C., Hebray, M., Collison, D., Garner, D., & Joule, J. (2005). A bis(η5-cyclopentadienyl)cobalt complex of a bis-dithiolene: a chemical analogue of the metal centres of the DMSO reductase family of molybdenum and tungsten enzymes, in particular ferredoxin aldehyde oxidoreductase. Tetrahedron Letters, 61(46), 11010-11019. https://doi.org/10.1016/j.tet.2005.08.095

@article{42cfd1b7b66f407daab1d16c01f0168f,

title = "A bis(η5-cyclopentadienyl)cobalt complex of a bis-dithiolene: a chemical analogue of the metal centres of the DMSO reductase family of molybdenum and tungsten enzymes, in particular ferredoxin aldehyde oxidoreductase",

abstract = "The synthesis is described of a bis-ene-1,2-dithiolate pro-ligand, designed to model the stereochemical situation in the cofactor of the tungsten enzyme ferredoxin aldehyde oxidoreductase from Pyrococcus furiosus. Each masked ene-1,2-dithiolate unit is mounted on a pyrano[2,3-b]tetrahydroquinoxaline tricycle, comparable to the pyrano[2,3-g]tetrahydropteridines found in all molybdoenzymes and tungsten analogues. Hydrolytic release of the bis-ligand was confirmed by its entrapment as a double (η5-C5H5)Co complex.",

keywords = "Aldehyde, Tungsten, Ligand, DMSO reductase family, Pyrano[2,3-b]quinoxaline, Enedithiolate",

author = "France-Aim{\'e}e Alphonse and Rehana Karim and C{\'e}line Cano-Soumillac and Marielle Hebray and David Collison and David Garner and John Joule",

year = "2005",

doi = "10.1016/j.tet.2005.08.095",

language = "English",

volume = "61",

pages = "11010--11019",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier",

number = "46",

}

Alphonse, F-A, Karim, R, Cano-Soumillac, C, Hebray, M, Collison, D, Garner, D & Joule, J 2005, 'A bis(η5-cyclopentadienyl)cobalt complex of a bis-dithiolene: a chemical analogue of the metal centres of the DMSO reductase family of molybdenum and tungsten enzymes, in particular ferredoxin aldehyde oxidoreductase', Tetrahedron Letters, cyfrol. 61, rhif 46, tt. 11010-11019. https://doi.org/10.1016/j.tet.2005.08.095

A bis(η5-cyclopentadienyl)cobalt complex of a bis-dithiolene: a chemical analogue of the metal centres of the DMSO reductase family of molybdenum and tungsten enzymes, in particular ferredoxin aldehyde oxidoreductase. / Alphonse, France-Aimée ; Karim, Rehana; Cano-Soumillac, Céline et al.

Yn: Tetrahedron Letters, Cyfrol 61, Rhif 46, 2005, t. 11010-11019.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

TY - JOUR

T1 - A bis(η5-cyclopentadienyl)cobalt complex of a bis-dithiolene: a chemical analogue of the metal centres of the DMSO reductase family of molybdenum and tungsten enzymes, in particular ferredoxin aldehyde oxidoreductase

AU - Alphonse, France-Aimée

AU - Karim, Rehana

AU - Cano-Soumillac, Céline

AU - Hebray, Marielle

AU - Collison, David

AU - Garner, David

AU - Joule, John

PY - 2005

Y1 - 2005

N2 - The synthesis is described of a bis-ene-1,2-dithiolate pro-ligand, designed to model the stereochemical situation in the cofactor of the tungsten enzyme ferredoxin aldehyde oxidoreductase from Pyrococcus furiosus. Each masked ene-1,2-dithiolate unit is mounted on a pyrano[2,3-b]tetrahydroquinoxaline tricycle, comparable to the pyrano[2,3-g]tetrahydropteridines found in all molybdoenzymes and tungsten analogues. Hydrolytic release of the bis-ligand was confirmed by its entrapment as a double (η5-C5H5)Co complex.

AB - The synthesis is described of a bis-ene-1,2-dithiolate pro-ligand, designed to model the stereochemical situation in the cofactor of the tungsten enzyme ferredoxin aldehyde oxidoreductase from Pyrococcus furiosus. Each masked ene-1,2-dithiolate unit is mounted on a pyrano[2,3-b]tetrahydroquinoxaline tricycle, comparable to the pyrano[2,3-g]tetrahydropteridines found in all molybdoenzymes and tungsten analogues. Hydrolytic release of the bis-ligand was confirmed by its entrapment as a double (η5-C5H5)Co complex.

KW - Aldehyde

KW - Tungsten

KW - Ligand

KW - DMSO reductase family

KW - Pyrano[2,3-b]quinoxaline

KW - Enedithiolate

U2 - 10.1016/j.tet.2005.08.095

DO - 10.1016/j.tet.2005.08.095

M3 - Article

VL - 61

SP - 11010

EP - 11019

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 46

ER -

Alphonse F-A, Karim R, Cano-Soumillac C, Hebray M, Collison D, Garner D et al. A bis(η5-cyclopentadienyl)cobalt complex of a bis-dithiolene: a chemical analogue of the metal centres of the DMSO reductase family of molybdenum and tungsten enzymes, in particular ferredoxin aldehyde oxidoreductase. Tetrahedron Letters. 2005;61(46):11010-11019. doi: 10.1016/j.tet.2005.08.095